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MilliporeSigma

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A Molecule’s Journey: Break Down Roadblocks to Commercial Manufacturing Success

In this guidebook, experts share key considerations for biopharmaceutical companies as they advance their antibody drug to commercial manufacturing.

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Build Quality into Biopharmaceutical Processes with Real-Time Monitoring and Control

The ability to monitor biopharma processes in real time provides significant advantages in optimizing product quality with respect to multiple attributes.

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Let’s Shape The Future Together.

In such a rapidly changing environment, it’s more important than ever to know who you can rely upon to help you succeed.

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Future-Proof Your Process with Modular Flexibility Today

MilliporeSigma unveils its new Mobius® iFlex Bioreactor family for fed-batch and perfusion upstream processes.

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Bridging the Sponsor – CMO Data Gulf

How do sponsors and CMOs realize the advantages of their partnership while avoiding the pitfalls of clunky data sharing?

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White Papers / Tech Papers

Improve Process Economics & Enable High Protein Concentrations

This whitepaper spotlights how excipient combinations can enhance manufacturability and final concentration of mAb formulations.

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Glucose Control in Cell Culture Using Raman

This automated approach minimizes the number of human interventions needed and reduces the risk of contamination and batch failures.

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Enhancing Ease of Use, Batch Turnaround, and Process Flexibility

The Pellicon® Capsule is the first of its kind—a true single-use TFF device that streamlines bioprocessing with its innovative, simplified design.

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White Papers / Tech Papers

Enhancement of Tablet Coating Using an Innovative Functional Excipient

This white paper describes key considerations and provides guidance on the preparation of a coating formulation.

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Explore the Next Generation Manufacturing of the Most Potent Compounds in Pharma

MilliporeSigma's new HPAPI contract manufacturing facility brings unmatched capacity to the market.

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White Papers / Tech Papers

Overcoming Challenges in Ophthalmic Formulations Through Polymer Selection

This white paper provides an overview of polymers that can be used in ophthalmic formulations and highlights advantages offered using polyvinyl alcohol (PVA).

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White Papers / Tech Papers

Regulatory Considerations for Excipients Used in Lipid Nanoparticles

This whitepaper provides an overview on the regulatory classification and emerging regulatory challenges for LNP, liposomes, and novel excipients.

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Challenges and Solutions in Viral Vector Manufacturing

The accelerated pathway through the clinic of viral vector-based cell and gene therapies puts pressure on developers to find a skilled partner.

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White Papers / Tech Papers

The Viscosity Reduction Platform: Viscosity-reducing excipients for protein formulation

This white paper evaluates the viscosity-reducing capacities of excipients and excipient combinations.

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Modification of Virus Spiking Procedures for Continuous Processes

This white paper demonstrates the feasibility of novel virus spiking strategies to meet the needs of continuous processes.

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