Avista Pharma Solutions, Inc. has completed the expansion and upgrades to its Analytical Laboratories at its Durham, NC facility. The investment significantly increases capacity as well as a range of capabilities for its pharmaceutical and medical device clients.
 
The Analytical Research and Development (ARD) and Quality Control (QC) labs have doubled in size and expanded the service offerings. The completed Analytical Laboratories’ systems and equipment include a Thermo Scientific Orbitrap High-Resolution Mass Spectrometer, Mass-Directed Preparative Chromatography, Agilent UPLC-tandem Quad MS, Waters H-class UPLCs with six-column switching capabilities and PDA/ELSD/CAD/Single Quad MS detectors, along with upgraded Laboratory Information Management System (LIMS), Empower 3 Chromatography Data Software and Agilent MassHunter software with Enterprise Content Manager.
 
“Expanding our laboratory and adding new service offerings reinforces our commitment to providing our clients with a world-class center of excellence to assist in their product development efforts,” said Patrick Walsh, chief executive officer at Avista. “Our clients choose to work with us because our skilled teams are relentless in support of their project needs.”
 
Avista’s full-service offering includes: Chromatographic method development for assay and related substances, potential genotoxic impurities, organic volatile impurities and residual solvents; Spectral identification using upgraded FTIR, NMR and UV-Vis instrumentation; Structural chemistry and impurity identification through accurate mass LC-MS and generation fragmentation (MSn), 1D and 2D NMR and preparative chromatography isolation; Fate and purge studies; Extractable/leachable studies; Release and stability testing.