GenScript Biotech Corporation, a provider of life-science research tools and services, added the AmMag Quatro automated plasmid purification system to its lab and research product line-up. The system is designed to streamline maxi-scale plasmid purification and reduce the manpower and time needed to purify high-quality, transfection-grade plasmid. Since its introduction, AmMag Quatro has been used in breakthrough projects such as viral vector development for cell engineering and gene therapy.

High-quality, transfection-ready plasmids are critical for the success of biologic research and development but traditional plasmid purification methods can be highly labor-intensive, inefficient, and prone to human or process errors. 

Demand for high-quality, transfection-grade plasmids has grown rapidly because plasmid DNA from bacteria is an essential component of genetic engineering and other biotechnology applications, such as cloning, transfection, and gene therapy. The need for an automated, large-scale plasmid purification solution has become increasingly evident.

According to the company, for research laboratories, the AmMag Quatro system is a game-changing addition to their arsenal of advanced equipment, offering scientists in academic, pharmaceutical and biotech settings a reliable and efficient way to purify high-quality, transfection-grade plasmids at scale; the AmMag Quatro system shortens the cycle of obtaining crucial plasmids through an efficient and expedient purification process.

The AmMag Quatro system encompasses a state-of-the-art controller capable of simultaneously operating up to four independent purification modules, along with pre-filled consumables and verified protocols. Each module can process up to six samples in one run, increasing throughput and efficiency. The system leverages magnetic bead technology and related reagents to automate the entire maxi-scale purification process, providing researchers with a reliable and efficient way to purify pDNA samples, reduce the risk of errors, and improve reproducibility.

“The AmMag Quatro has become a powerful tool for researchers to advance their work, and we are thrilled to see the impact it has had on the scientific community since its introduction,” said Hong Qian, COO of the Life Science Group and general manager of GenScript Inc. Products Division.

“Since we started using the AmMag Quatro, our workflow has been transformed,” said Zhonghua Zhu, head of vector development and cell engineering at TScan Therapeutics. “We no longer need dedicated personnel for manual work, and we can customize the parameters for DNA prep to optimize our results. This cutting-edge system has transformed TScan’s workflow, increasing efficiency and throughput.”