Syntegon (formerly Bosch Packaging Technology) will showcase new solutions for lab-scale and small batch filling of solid and liquid pharmaceuticals at Interphex booth 3139: The new GKF 60 capsule filling machine and the Versynta Flexible Filling Platform (FFP). “The need for smaller quantities of highly potent drugs is rising continuously. We have put these solutions in the focus of our current development activities and are proud to offer our customers a number of exciting new technologies,” said Thomas Mauritzen, General Manager at Syntegon Minneapolis.  
 

GKF 60: new standards in capsule filling for laboratories
The new GKF 60 capsule filling machine enables the development of new formulations with a wide variety of dosing systems at different OEB levels and with an optional 100 percent gravimetric weighing system. The mobile machine with only six stations requires little space and few format parts. Familiar dosing modules for DPI, pellets, tablets, or liquids, as well as the mini-bowl station for scale-up to the next larger production machine offer flexibility. Also, the newly developed piezo dosing station makes it possible to accurately fill very small quantities starting at 0.1 milligram filling weight. Customers can choose between a standard, a containment and a combi solution. The latter can be adapted for both simple and highly potent formulations up to OEB5 high-containment.

 
Versynta FFP: modular small batch solution for liquid pharmaceuticals
Syntegon’s Versynta FFP was developed for highly potent pharmaceuticals. The modular and individually configurable small batch solution for liquid pharmaceuticals with an integrated isolator is designed to achieve precise product yields at low output. The platform is based on pre-developed and tested modules that can be flexibly combined. It handles different container types such as vials, syringes, and cartridges, and can be converted to different filling systems including single-use solutions. The Pharma Handling Unit, a four-axis robot allows for safe and gentle transport without glass-to-glass contact. Versynta FFP processes up to 3,600 containers per hour and comes with 100 percent in-process control.

The portfolio includes a comprehensive consulting and service offering along the entire machine lifecycle. Offerings range from spare parts and field service to stock optimization, modernization and preventive maintenance, as well as remote and data-based services. As of November, all Syntegon machines will be delivered “IoT ready” and provide interfaces for numerous digital solutions.