Triclinic Labs and Eldico Scientific have entered an exclusive strategic collaboration to introduce Microcrystal Electron Diffraction services and instruments to the North American market.
 
Microcrystal Electron Diffraction (microED, also called 3D ED) has emerged as a way to bridge the deficiencies between single-crystal X-ray diffraction (SCXRD) and powder X-ray diffraction (PXRD). It can be utilized for crystals that are orders of magnitude smaller than required for SCXRD and with much smaller sample amounts than required for PXRD.
 
Under the terms of the agreement, Triclinic Labs has installed Eldico’s MicroED instrument, the ED-1, at its labs in Indiana. Using the ED-1 and software, Triclinic’s crystallography group will offer crystal structure determination from nanocrystalline powders, absolute configuration determination, micro-crystallinity analysis in amorphous solid dispersions, and phase analysis of crystals in mixtures. Triclinic is the only contract research provider in North America to offer MicroED analysis using the system.
 
“We’re incredibly excited to add Eldico’s instrument and software to our powder and single crystal diffraction capabilities. It bridges a huge gap in the pharmaceutical and specialty chemical industries,” said Dr. Steef Boerrigter, Triclinic’s Head of Materials Modeling. “The ED-1 system bypasses one of the main limitations of crystallography, namely – growing crystals of suitable size. The ED-1 system also overcomes the limitations of older Cryo-TEM systems,” he added.
 
“We are thrilled to bring our innovative microED instrument to the North American market for mainstream application,” said Danny Stam, Sales Manager at Eldico Scientific. “Our potential clients have indicated a US laboratory with Triclinic’s reputation and proximity will allow the technique to be more quickly adopted in research and patent projects. This collaboration will demonstrate the utility and ease of use of the ED-1, which can be used as a new crystallography tool during chemical and intellectual property development.”