It allows multiparametric analysis of thousands of particles per second and helps to identify or functionally characterize complex cell populations of interest.

Flow cytometry is a versatile technology for developing drug-specific assays. It is often used in basic research, discovery, preclinical and clinical trials. With the increasing proportion of biologics in the pipeline, flow cytometry has proven itself to be an indispensable tool in many cases to assess safety (immunophenotyping, functional assays), receptor occupancy or pharmacodynamics (functional assays).

The expert scientific staff at Charles River provides services for flow cytometry method transfer, method development, method validation, and high-quality sample analysis and interpretation in accordance with applicable clinical GLP or GCP requirements. Furthermore, our scientists can develop novel flow cytometric assays as needed, if appropriate reagents are available, that can be carried through from discovery to the clinical phase. Fluorochrome conjugation services are also available if the reagent is not available commercially.