Features

Top 50 (or so) Biopharma Products

Ranking the top 57 biopharma products by 2011 revenues

By: Ronald a rader

Biotechnology Information Institute

For our Top Companies issue, we asked Ronald A. Rader, president of the Biotechnology Information Institute, to provide a list of the Top 57 Biopharma Products by 2011 revenues (in millions). Mr. Rader subscribes to the same criteria as Contract Pharma — that biopharmaceuticals are pharmaceuticals manufactured by living organisms (involving biotechnology/bioprocessing), including recombinant and non-recombinant proteins, antibodies and vaccines.  Thus, “If it’s small molecule, it ain’t biopharma!”

About the Author
Ronald A. Rader is a consultant and the author and publisher of BIOPHARMA: Biopharmaceutical Products in the U.S. and European Markets (www.biopharma.com),
the only information resource/reference specializing in biopharmaceuticals. The Biotechnology Information Institute is located in Rockville, MD. Mr. Rader may be contacted at biotech@biopharma.com

Trade Name

Description

Marketer

2011 Revenues

Humira

TNF Mab, rDNA, human

Abbott

$7,932

Enbrel

TNF Receptor-IgG Fc, rDNA

Amgen, Pfizer

$7,870

Remicade

TNF Mab, rDNA

J&J, Merck

$7,157

Avastin

VEGF Mab, rDNA

Genentech/Roche

$6,596

Rituxan

CD20 Mab, rDNA

Genentech/Roche, Biogen Idec

$6,596

Herceptin

HER2 receptor Mab, rDNA

Genentech/Roche

$5,770

Lantus

Insulin glargine, rDNA

Sanofi

$5,190

Neulasta

G-CSF, rDNA, PEG-

Amgen, Roche

$3,950

Epogen/Procrit

EPO, rDNA

Amgen, J&J

$3,730

Lucentis

VEGF Mab Fab, rDNA

Genentech/Roche, Novartis

$3,723

Prevnar 13

Pneumococcal Vaccine(13)-CRM197

Pfizer

$3,330

Aranesp

EPO, darbo-, rDNA

Amgen

$2,997

Avonex

Interferon beta-1a, rDNA

Biogen Idec, Merck

$2,700

Humalog

Insulin lispro, rDNA

Lilly, Roche

$2,367

NovoLog

Insulin aspart, rDNA

Novo Nordisk

$2,274

Rebif

Interferon beta-1a, rDNA

Merck KGaA

$2,235

Advate

Factor VIII, rDNA

Baxter

$2,210

Novolin

Insulin, rDNA

Novo Nordisk

$1,916

Erbitux

EGF receptor Mab, rDNA

Bristol-Myers Squibb

$1,820

Botox

Botulinum Toxin A

Allergan

$1,775

Tysabri

Integrin Mab, rDNA

Biogen Idec, Elan

$1,500

Pegasys

Interferon alfa-2a, rDNA, PEG-

Roche

$1,476

Betaseron

Interferon betaser, rDNA

Bayer

$1,476

NovoSeven

Factor VIIa, rDNA

Novo Nordisk

$1,470

Neupogen

G-CSF, rDNA

Amgen & Roche

$1,440

Kogenate

Factor VIII, rDNA

Bayer

$1,420

Levemir

Insulin detemir, rDNA

Novo Nordisk

$1,365

Humulin

Insulin, rDNA/Lilly

Lilly

$1,249

Gardasil

HPV vaccine, rDNA

Merck

$1,209

Xolair

Immunoglobulin E Mab, rDNA

Genentech/Roche, Novartis

$1,140

Victoza

Glucagon-like peptide-1, rDNA

Novo Nordisk

$1,060

NeoRecormon

EPO beta, rDNA

Roche

$985

Synagis

RSV Mab, rDNA

MedImmune/AstraZeneca

$980

Varivax II

Varicella virus vaccine

Merck

$975

Fortéo

Parathyroid hormone (1-34), rDNA

Lilly

$950

Genotropin

Somatropin, rDNA

Pfizer

$940

Orencia

CTLA4-Ig, rDNA

Bristol-Myers Squibb

$917

Norditropin

Somatropin, rDNA

Novo Nordisk

$890

Eprex

EPO, rDNA

J&J

$809

Soliris

Complement C5 Mab, rDNA

Alexion

$783

Stelara

IL-12/23 Mab, rDNA

J&J

$740

Cerezyme

Glucocerebrosidase, rDNA

Genzyme/Sanofi

$720

BeneFIX

Factor IX, rDNA

Pfizer

$695

Actemra

IL-6 receptor Mab, rDNA

Genentech/Roche

$680

Simponi

TNF Mab, rDNA

J&J

$674

PEG-Intron

Interferon alfa-2b, rDNA, PEG-

Merck

$657

RotaTeq

Rotavirus vaccine

Merck

$651

Gonal-f

FSH rDNA

Merck KGaA

$645

Myozyme

Glucosidase, rDNA

Genzyme/Sanofi

$543

Pulmozyme

DNase, rDNA

Genentech/Roche

$540

Menactra

Meningococcal vaccine

Sanofi

$530

Follistim

FSH rDNA

Merck

$530

Lumizyme

Glucosidase, rDNA

Genzyme/Sanofi

$530

Vectibix

EGF receptor Mab, human, rDNA

Amgen

$525

Xyntha/ReFacto

Factor VIII, rDNA

Pfizer

$504

Recombivax HB

Hepatitis B Vaccine, rDNA

Merck

$500

Engerix-B

Hepatitis B Vaccine, rDNA

GlaxoSmithKline

$500

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